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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIKFYVE
All Species:
10
Human Site:
S921
Identified Species:
24.44
UniProt:
Q9Y2I7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2I7
NP_055855.2
2098
237108
S921
D
P
D
I
P
P
E
S
L
P
C
D
D
S
S
Chimpanzee
Pan troglodytes
XP_516057
2098
237088
S921
D
P
D
I
P
P
E
S
L
P
C
D
D
S
S
Rhesus Macaque
Macaca mulatta
XP_001108540
2098
237142
S921
D
P
D
I
P
P
E
S
L
P
C
D
D
S
S
Dog
Lupus familis
XP_536048
2100
237099
L922
E
P
D
F
P
P
E
L
L
P
S
D
D
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T6
2097
236858
A921
D
P
E
C
P
R
E
A
L
S
S
E
D
S
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508087
1539
172614
L437
D
S
A
A
S
I
S
L
N
V
E
L
D
N
V
Chicken
Gallus gallus
XP_421967
2112
239039
S924
E
I
R
D
V
E
P
S
A
E
K
L
P
A
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O96838
1809
204617
R707
L
F
A
R
Y
N
W
R
L
E
M
S
F
L
L
Honey Bee
Apis mellifera
XP_393666
1986
224732
V870
S
S
I
L
S
E
D
V
D
P
Y
D
T
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34756
2278
257401
I1102
S
P
T
V
D
F
P
I
P
F
L
L
E
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
95.2
N.A.
93.5
N.A.
N.A.
53.9
86.2
N.A.
N.A.
N.A.
28.7
34.1
N.A.
N.A.
Protein Similarity:
100
99.9
99.4
97
N.A.
96.3
N.A.
N.A.
60.2
91.5
N.A.
N.A.
N.A.
46.1
53.5
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
46.6
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
6.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
10
0
0
0
10
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
30
0
0
0
0
% C
% Asp:
50
0
40
10
10
0
10
0
10
0
0
50
60
0
0
% D
% Glu:
20
0
10
0
0
20
50
0
0
20
10
10
10
0
0
% E
% Phe:
0
10
0
10
0
10
0
0
0
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
30
0
10
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% K
% Leu:
10
0
0
10
0
0
0
20
60
0
10
30
0
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
60
0
0
50
40
20
0
10
50
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
20
20
0
0
20
0
10
40
0
10
20
10
0
50
30
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% T
% Val:
0
0
0
10
10
0
0
10
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _